MEL-18 prevents the brand new SUMOylation off p53 and you will SP1 to lead to ESR1 expression
MEL-18 prevents the brand new SUMOylation off p53 and you will SP1 to lead to ESR1 expression The proximal promoter region of ESR1, that is managed because of the MEL-18, include joining sites for a couple epigenetic and transcription facts ( 30 , thirty two ). Although not, no significant difference on the phrase off […]